RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status

More than 30% of all human cancers are driven by RAS mutations and activating KRAS mutations are present in 40% of colorectal cancer (CRC) in the two main CRC subgroups, MSS (Microsatellite Stable) and MSI (Microsatellite Instable). Studies in RAS-driven tumors have shown essential roles of the RAS...

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Detalles Bibliográficos
Autores principales: Dorard, Coralie, Madry, Claire, Buhard, Olivier, Toifl, Stefanie, Didusch, Sebastian, Ratovomanana, Toky, Letourneur, Quentin, Dolznig, Helmut, Garnett, Mathew J., Duval, Alex, Baccarini, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181936/
https://www.ncbi.nlm.nih.gov/pubmed/37020037
http://dx.doi.org/10.1038/s41388-023-02683-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181936/
https://www.ncbi.nlm.nih.gov/pubmed/37020037
http://dx.doi.org/10.1038/s41388-023-02683-w

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