Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Mechanisms underpinning the dysfunctional immune response in severe acute respiratory syndrome coronavirus 2 infection are elusive. We analyzed single-cell transcriptomes and T and B cell receptors (BCR) of >895,000 peripheral blood mononuclear cells from 73 coronavirus disease 2019 (COVID-19) pa...

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Detalles Bibliográficos
Autores principales: Edahiro, Ryuya, Shirai, Yuya, Takeshima, Yusuke, Sakakibara, Shuhei, Yamaguchi, Yuta, Murakami, Teruaki, Morita, Takayoshi, Kato, Yasuhiro, Liu, Yu-Chen, Motooka, Daisuke, Naito, Yoko, Takuwa, Ayako, Sugihara, Fuminori, Tanaka, Kentaro, Wing, James B., Sonehara, Kyuto, Tomofuji, Yoshihiko, Namkoong, Ho, Tanaka, Hiromu, Lee, Ho, Fukunaga, Koichi, Hirata, Haruhiko, Takeda, Yoshito, Okuzaki, Daisuke, Kumanogoh, Atsushi, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181941/
https://www.ncbi.nlm.nih.gov/pubmed/37095364
http://dx.doi.org/10.1038/s41588-023-01375-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181941/
https://www.ncbi.nlm.nih.gov/pubmed/37095364
http://dx.doi.org/10.1038/s41588-023-01375-1

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