Lactoferrin and its digestive peptides induce interferon-α production and activate plasmacytoid dendritic cells ex vivo

Plasmacytoid dendritic cells (pDCs) recognise viral single-stranded RNA (ssRNA) or CpG DNA via Toll-like receptor (TLR)-7 and TLR9, and produce interferon (IFN)-α. Activated pDCs upregulate human leukocyte antigen (HLA)-DR and CD86 expression levels. Ingestion of bovine lactoferrin (LF) activates pD...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubo, Shutaro, Miyakawa, Momoko, Tada, Asuka, Oda, Hirotsugu, Motobayashi, Hideki, Iwabuchi, Sadahiro, Tamura, Shinobu, Tanaka, Miyuki, Hashimoto, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181974/
https://www.ncbi.nlm.nih.gov/pubmed/36018422
http://dx.doi.org/10.1007/s10534-022-00436-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181974/
https://www.ncbi.nlm.nih.gov/pubmed/36018422
http://dx.doi.org/10.1007/s10534-022-00436-y

Ejemplares similares