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Discovery of two new isoforms of the human DUT gene

In human cells two dUTPase isoforms have been described: one nuclear (DUT-N) and one mitochondrial (DUT-M), with cognate localization signals. In contrast, here we identified two additional isoforms; DUT-3 without any localization signal and DUT-4 with the same nuclear localization signal as DUT-N....

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Detalles Bibliográficos
Autores principales: Rácz, Gergely Attila, Nagy, Nikolett, Várady, György, Tóvári, József, Apáti, Ágota, Vértessy, Beáta G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181998/
https://www.ncbi.nlm.nih.gov/pubmed/37173337
http://dx.doi.org/10.1038/s41598-023-32970-1