Prediction of mammalian tissue-specific CLOCK–BMAL1 binding to E-box DNA motifs

The Brain and Muscle ARNTL-Like 1 protein (BMAL1) forms a heterodimer with either Circadian Locomotor Output Cycles Kaput (CLOCK) or Neuronal PAS domain protein 2 (NPAS2) to act as a master regulator of the mammalian circadian clock gene network. The dimer binds to E-box gene regulatory elements on...

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Detalles Bibliográficos
Autores principales: Marri, Daniel, Filipovic, David, Kana, Omar, Tischkau, Shelley, Bhattacharya, Sudin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182026/
https://www.ncbi.nlm.nih.gov/pubmed/37173345
http://dx.doi.org/10.1038/s41598-023-34115-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182026/
https://www.ncbi.nlm.nih.gov/pubmed/37173345
http://dx.doi.org/10.1038/s41598-023-34115-w

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