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Prediction of mammalian tissue-specific CLOCK–BMAL1 binding to E-box DNA motifs
The Brain and Muscle ARNTL-Like 1 protein (BMAL1) forms a heterodimer with either Circadian Locomotor Output Cycles Kaput (CLOCK) or Neuronal PAS domain protein 2 (NPAS2) to act as a master regulator of the mammalian circadian clock gene network. The dimer binds to E-box gene regulatory elements on...
Autores principales: | Marri, Daniel, Filipovic, David, Kana, Omar, Tischkau, Shelley, Bhattacharya, Sudin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182026/ https://www.ncbi.nlm.nih.gov/pubmed/37173345 http://dx.doi.org/10.1038/s41598-023-34115-w |
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