A first-in-class inhibitor of Hsp110 molecular chaperones of pathogenic fungi

Proteins of the Hsp110 family are molecular chaperones that play important roles in protein homeostasis in eukaryotes. The pathogenic fungus Candida albicans, which causes infections in humans, has a single Hsp110, termed Msi3. Here, we provide proof-of-principle evidence supporting fungal Hsp110s a...

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Detalles Bibliográficos
Autores principales: Hu, Liqing, Sun, Cancan, Kidd, Justin M., Han, Jizhong, Fang, Xianjun, Li, Hongtao, Liu, Qingdai, May, Aaron E., Li, Qianbin, Zhou, Lei, Liu, Qinglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182041/
https://www.ncbi.nlm.nih.gov/pubmed/37173314
http://dx.doi.org/10.1038/s41467-023-38220-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182041/
https://www.ncbi.nlm.nih.gov/pubmed/37173314
http://dx.doi.org/10.1038/s41467-023-38220-2

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