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Design, synthesis and anticancer activities evaluation of novel pyrazole modified catalpol derivatives

Catalpol, a natural product mainly existed in plenty of Chinese traditional medicines, is an iridoid compound with the comprehensive effects on neuroprotective, anti-inflammatory, choleretic, hypoglycemic and anticancer. However, there are some disadvantages for catalpol such as a short half-life in...

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Detalles Bibliográficos
Autores principales: Kong, Yuanfang, Liu, Shuanglin, Wang, Shaopei, Yang, Bin, He, Wei, Li, Hehe, Yang, Siqi, Wang, Guoqing, Dong, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182059/
https://www.ncbi.nlm.nih.gov/pubmed/37173367
http://dx.doi.org/10.1038/s41598-023-33403-9