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Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice

Phosphatidylcholine transfer protein (PC-TP; synonym StarD2) is a soluble lipid-binding protein that transports phosphatidylcholine (PC) between cellular membranes. To better understand the protective metabolic effects associated with hepatic PC-TP, we generated a hepatocyte-specific PC-TP knockdown...

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Detalles Bibliográficos
Autores principales: Druzak, Samuel A., Tardelli, Matteo, Mays, Suzanne G., El Bejjani, Mireille, Mo, Xulie, Maner-Smith, Kristal M., Bowen, Thomas, Cato, Michael L., Tillman, Matthew C., Sugiyama, Akiko, Xie, Yang, Fu, Haian, Cohen, David E., Ortlund, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182070/
https://www.ncbi.nlm.nih.gov/pubmed/37173315
http://dx.doi.org/10.1038/s41467-023-38010-w