Cdc14 phosphatase counteracts Cdk-dependent Dna2 phosphorylation to inhibit resection during recombinational DNA repair

Cyclin-dependent kinase (Cdk) stimulates resection of DNA double-strand breaks ends to generate single-stranded DNA (ssDNA) needed for recombinational DNA repair. Here we show in Saccharomyces cerevisiae that lack of the Cdk-counteracting phosphatase Cdc14 produces abnormally extended resected tract...

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Detalles Bibliográficos
Autores principales: Campos, Adrián, Ramos, Facundo, Iglesias, Lydia, Delgado, Celia, Merino, Eva, Esperilla-Muñoz, Antonio, Correa-Bordes, Jaime, Clemente-Blanco, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182099/
https://www.ncbi.nlm.nih.gov/pubmed/37173316
http://dx.doi.org/10.1038/s41467-023-38417-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182099/
https://www.ncbi.nlm.nih.gov/pubmed/37173316
http://dx.doi.org/10.1038/s41467-023-38417-5

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