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Clinical Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anifrolumab
The type I interferon (IFN) signaling pathway is implicated in the pathogenesis of systemic lupus erythematosus (SLE). Anifrolumab is a monoclonal antibody that targets the type I IFN receptor subunit 1. Anifrolumab is approved in several countries for patients with moderate to severe SLE receiving...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182164/ https://www.ncbi.nlm.nih.gov/pubmed/37148484 http://dx.doi.org/10.1007/s40262-023-01238-2 |