AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity

Metabolic alterations are important cancer-associated features that allow cancer cell transformation and survival under stress conditions. Multiple myeloma (MM) plasma cells show increased glycolysis and oxidative phosphorylation (OXPHOS), which are characteristics associated with recurrent genetic...

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Detalles Bibliográficos
Autores principales: Bloedjes, Timon A., de Wilde, Guus, Khan, Gerarda H., Ashby, Timothy C., Shaughnessy, John D., Zhan, Fenghuang, Houtkooper, Riekelt H., Bende, Richard J., van Noesel, Carel J. M., Spaargaren, Marcel, Guikema, Jeroen E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182179/
https://www.ncbi.nlm.nih.gov/pubmed/36322819
http://dx.doi.org/10.1182/bloodadvances.2022007383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182179/
https://www.ncbi.nlm.nih.gov/pubmed/36322819
http://dx.doi.org/10.1182/bloodadvances.2022007383

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