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Overexpression of the lncRNA HOTAIRM1 promotes lenvatinib resistance by downregulating miR-34a and activating autophagy in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant cancers in humans and has a high fatality rate. Despite pharmacological advances such as sorafenib and lenvatinib approval, responses are seen only in a limited fraction of HCCs, and the majority of HCC patients do not be...

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Detalles Bibliográficos
Autores principales: Gu, Danyan, Tong, Meng, Wang, Jing, Zhang, Bocheng, Liu, Jinghua, Song, Guoqiang, Zhu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182232/
https://www.ncbi.nlm.nih.gov/pubmed/37171645
http://dx.doi.org/10.1007/s12672-023-00673-8