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Dysregulated brain regulatory T cells fail to control reactive gliosis following repeated antigen stimulation
This study was undertaken to investigate the role of CD4+FoxP3+ regulatory T cells (Tregs) in regulating neuroinflammation during viral Ag-challenge and re-challenge. CD8(+) lymphocytes persisting within tissues are designated tissue-resident memory T cells (T(RM)), within brain: bT(RM). Reactivatio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182273/ https://www.ncbi.nlm.nih.gov/pubmed/37192971 http://dx.doi.org/10.1016/j.isci.2023.106628 |