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Dysregulated brain regulatory T cells fail to control reactive gliosis following repeated antigen stimulation

This study was undertaken to investigate the role of CD4+FoxP3+ regulatory T cells (Tregs) in regulating neuroinflammation during viral Ag-challenge and re-challenge. CD8(+) lymphocytes persisting within tissues are designated tissue-resident memory T cells (T(RM)), within brain: bT(RM). Reactivatio...

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Detalles Bibliográficos
Autores principales:	Prasad, Sujata, Singh, Amar, Hu, Shuxian, Sheng, Wen S., Chauhan, Priyanka, Lokensgard, James R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182273/ https://www.ncbi.nlm.nih.gov/pubmed/37192971 http://dx.doi.org/10.1016/j.isci.2023.106628

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