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Toward a systems-level probing of tumor clonality

Cancer has been described as a genetic disease that clonally evolves in the face of selective pressures imposed by cell-intrinsic and extrinsic factors. Although classical models based on genetic data predominantly propose Darwinian mechanisms of cancer evolution, recent single-cell profiling of can...

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Detalles Bibliográficos
Autores principales: Grody, Emanuelle I., Abraham, Ajay, Shukla, Vipul, Goyal, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182304/
https://www.ncbi.nlm.nih.gov/pubmed/37192968
http://dx.doi.org/10.1016/j.isci.2023.106574