Kindlin-3 deficiency leads to impaired erythropoiesis and erythrocyte cytoskeleton

Kindlin-3 (K3) is critical for the activation of integrin adhesion receptors in hematopoietic cells. In humans and mice, K3 deficiency is associated with impaired immunity and bone development, bleeding, and aberrant erythrocyte shape. To delineate how K3 deficiency (K3KO) contributes to anemia and...

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Detalles Bibliográficos
Autores principales: Szpak, Dorota, Turpin, Chloe, Goreke, Utku, Bialkowska, Katarzyna, Bledzka, Kamila M., Verbovetskiy, Dmitriy, Mohandas, Narla, Gurkan, Umut A., Qin, Jun, Plow, Edward F., Pluskota, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182306/
https://www.ncbi.nlm.nih.gov/pubmed/36649586
http://dx.doi.org/10.1182/bloodadvances.2022008498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182306/
https://www.ncbi.nlm.nih.gov/pubmed/36649586
http://dx.doi.org/10.1182/bloodadvances.2022008498

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