A scalable workflow to test “shock and kill” therapeutic approaches against the HIV-1 latent reservoir in blood cells ex vivo

Integrated HIV-1 DNA persists in cells of people living with HIV during antiretroviral treatment, but its quantification is hindered by its rarity. Here, we present an optimized protocol to evaluate “shock and kill” therapeutic strategies, including both the latency reactivation (“shock”) and elimin...

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Detalles Bibliográficos
Autores principales: Procopio, Francesco Andrea, Savarino, Andrea, Shytaj, Iart Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182335/
https://www.ncbi.nlm.nih.gov/pubmed/37097819
http://dx.doi.org/10.1016/j.xpro.2023.102253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182335/
https://www.ncbi.nlm.nih.gov/pubmed/37097819
http://dx.doi.org/10.1016/j.xpro.2023.102253

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