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Effect of DNA aptamer through blocking of negative regulation of Wnt/β‐catenin signaling in human hair follicle dermal papilla cells

BACKGROUND: When Wnt binds to the N‐terminal of Frizzled, a conformational change occurs in the C‐terminal of Frizzled, which binds to Dishevelled1 (Dvl1), a Wnt signaling component protein. When Dvl1 binds to the C‐terminal of Frizzled, the concentration of β‐catenin increases and it enters the nuc...

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Detalles Bibliográficos
Autores principales: Won, Areum, Choi, Sooho, Kim, A‐Ru, Hong, Junkee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182398/
https://www.ncbi.nlm.nih.gov/pubmed/37231925
http://dx.doi.org/10.1111/srt.13326