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Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin

[Image: see text] Introduction: Fingolimod is a drug that is used to treat multiple sclerosis (MS). It has pH-dependent solubility and low solubility when buffering agents are present. Multi-spectroscopic and molecular modeling methods were used to investigate the molecular mechanism of Fingolimod i...

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Detalles Bibliográficos
Autores principales: Gholizadeh, Samira, Haghaei, Hossein, Karami, Hosna, Soltani, Somaieh, Zakariazadeh, Mostafa, Shokri, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences (TUOMS Publishing Group) 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182447/
https://www.ncbi.nlm.nih.gov/pubmed/37193080
http://dx.doi.org/10.34172/bi.2022.23383