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Intranasal COVID-19 vaccine induces respiratory memory T cells and protects K18-hACE mice against SARS-CoV-2 infection

Current COVID-19 vaccines prevent severe disease, but do not induce mucosal immunity or prevent infection with SARS-CoV-2, especially with recent variants. Furthermore, serum antibody responses wane soon after immunization. We assessed the immunogenicity and protective efficacy of an experimental CO...

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Detalles Bibliográficos
Autores principales: Diallo, Béré K., Ní Chasaide, Caitlín, Wong, Ting Y., Schmitt, Pauline, Lee, Katherine S., Weaver, Kelly, Miller, Olivia, Cooper, Melissa, Jazayeri, Seyed D., Damron, F. Heath, Mills, Kingston H. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182552/
https://www.ncbi.nlm.nih.gov/pubmed/37179389
http://dx.doi.org/10.1038/s41541-023-00665-3