LINC00963-FOSB-mediated transcription activation of UBE3C enhances radioresistance of breast cancer cells by inducing ubiquitination-dependent protein degradation of TP73

BACKGROUND: The ubiquitin protein ligase E3C (UBE3C) has been reported to play an oncogenic role in breast cancer (BRCA). This work further investigates the effect of UBE3C on the radioresistance of BRCA cells. METHODS: Molecules linking to radioresistance in BRCA were identified by analyzing two GE...

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Detalles Bibliográficos
Autores principales: Wang, Yansu, Liu, Ming, Liu, Xiaoqian, Guo, Xianling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182610/
https://www.ncbi.nlm.nih.gov/pubmed/37173692
http://dx.doi.org/10.1186/s12967-023-04153-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182610/
https://www.ncbi.nlm.nih.gov/pubmed/37173692
http://dx.doi.org/10.1186/s12967-023-04153-z

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