The PI3K-Akt-mTOR pathway mediates renal pericyte-myofibroblast transition by enhancing glycolysis through HKII

BACKGROUND: Pericyte-myofibroblast transition (PMT) has been confirmed to contribute to renal fibrosis in several kidney diseases, and transforming growth factor-β1 (TGF-β1) is a well-known cytokine that drives PMT. However, the underlying mechanism has not been fully established, and little is know...

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Detalles Bibliográficos
Autores principales: Chen, Liangmei, Li, Xiaofan, Deng, Yiyao, Chen, Jianwen, Huang, Mengjie, Zhu, Fengge, Gao, Zhumei, Wu, Lingling, Hong, Quan, Feng, Zhe, Cai, Guangyan, Sun, Xuefeng, Bai, Xueyuan, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182641/
https://www.ncbi.nlm.nih.gov/pubmed/37179292
http://dx.doi.org/10.1186/s12967-023-04167-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182641/
https://www.ncbi.nlm.nih.gov/pubmed/37179292
http://dx.doi.org/10.1186/s12967-023-04167-7

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