Integration of ATAC-Seq and RNA-Seq reveals FOSL2 drives human liver progenitor-like cell aging by regulating inflammatory factors

BACKGROUND: Human primary hepatocytes (PHCs) are considered to be the best cell source for cell-based therapies for the treatment of end-stage liver disease and acute liver failure. To obtain sufficient and high-quality functional human hepatocytes, we have established a strategy to dedifferentiate...

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Detalles Bibliográficos
Autores principales: Ding, Min, Huang, Weijian, Liu, Guifen, Zhai, Bo, Yan, Hexin, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182660/
https://www.ncbi.nlm.nih.gov/pubmed/37173651
http://dx.doi.org/10.1186/s12864-023-09349-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182660/
https://www.ncbi.nlm.nih.gov/pubmed/37173651
http://dx.doi.org/10.1186/s12864-023-09349-7

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