Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation

BACKGROUND: Kaixin Jieyu Granule (KJG), an improved formula of Kai-xin-san and Si-ni-san, is a highly effective formula with demonstrated efficacy in preventing depression in previous studies. However, the underlying molecular mechanisms of KJG’s antidepressant effects on inflammatory molecules rema...

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Detalles Bibliográficos
Autores principales: Xu, Manman, Zhai, Wujianwen, Zhang, Ying, Pan, Juhua, Li, Jie, Huang, Shijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182664/
https://www.ncbi.nlm.nih.gov/pubmed/37173696
http://dx.doi.org/10.1186/s12906-023-03970-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182664/
https://www.ncbi.nlm.nih.gov/pubmed/37173696
http://dx.doi.org/10.1186/s12906-023-03970-5

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