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Kaixin Jieyu Granule attenuates neuroinflammation-induced depressive-like behavior through TLR4/PI3K/AKT/FOXO1 pathway: a study of network pharmacology and experimental validation

BACKGROUND: Kaixin Jieyu Granule (KJG), an improved formula of Kai-xin-san and Si-ni-san, is a highly effective formula with demonstrated efficacy in preventing depression in previous studies. However, the underlying molecular mechanisms of KJG’s antidepressant effects on inflammatory molecules rema...

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Detalles Bibliográficos
Autores principales:	Xu, Manman, Zhai, Wujianwen, Zhang, Ying, Pan, Juhua, Li, Jie, Huang, Shijing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182664/ https://www.ncbi.nlm.nih.gov/pubmed/37173696 http://dx.doi.org/10.1186/s12906-023-03970-5

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