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Butyrate inhibits iILC2-mediated lung inflammation via lung-gut axis in chronic obstructive pulmonary disease (COPD)

BACKGROUND: The study investigated the effects and underlying mechanisms of intestinal flora metabolite butyrate on inflammatory ILC2 cells (iILC2s)-mediated lung inflammation in chronic obstructive pulmonary disease (COPD). METHODS: Mouse models of COPD and acute exacerbation of COPD (AECOPD) were...

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Detalles Bibliográficos
Autores principales: Jiang, Min, Li, Zhiwei, Zhang, Fengbo, Li, Zheng, Xu, Dan, Jing, Jing, Li, Fengsen, Wang, Jing, Ding, Jianbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182695/
https://www.ncbi.nlm.nih.gov/pubmed/37173731
http://dx.doi.org/10.1186/s12890-023-02438-z