Effective design and inference for cell sorting and sequencing based massively parallel reporter assays

MOTIVATION: The ability to measure the phenotype of millions of different genetic designs using Massively Parallel Reporter Assays (MPRAs) has revolutionized our understanding of genotype-to-phenotype relationships and opened avenues for data-centric approaches to biological design. However, our kno...

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Detalles Bibliográficos
Autores principales: Gilliot, Pierre-Aurélien, Gorochowski, Thomas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182853/
https://www.ncbi.nlm.nih.gov/pubmed/37084251
http://dx.doi.org/10.1093/bioinformatics/btad277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182853/
https://www.ncbi.nlm.nih.gov/pubmed/37084251
http://dx.doi.org/10.1093/bioinformatics/btad277

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