The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice

Mutations in GJB2 (Gap junction protein beta 2) are the most common genetic cause of non-syndromic hereditary deafness in humans, especially the 35delG and 235delC mutations. Owing to the homozygous lethality of Gjb2 mutations in mice, there are currently no perfect mouse models carrying Gjb2 mutati...

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Detalles Bibliográficos
Autores principales: Li, Qing, Cui, Chong, Liao, Rongyu, Yin, Xidi, Wang, Daqi, Cheng, Yanbo, Huang, Bowei, Wang, Liqin, Yan, Meng, Zhou, Jinan, Zhao, Jingjing, Tang, Wei, Wang, Yingyi, Wang, Xiaohan, Lv, Jun, Li, Jinsong, Li, Huawei, Shu, Yilai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182940/
https://www.ncbi.nlm.nih.gov/pubmed/37178259
http://dx.doi.org/10.1007/s00018-023-04794-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182940/
https://www.ncbi.nlm.nih.gov/pubmed/37178259
http://dx.doi.org/10.1007/s00018-023-04794-9

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