Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved

Toxicity studies, among them hepatotoxicity, are key throughout preclinical stages of drug development to minimise undesired toxic effects that might eventually appear in the course of the clinical use of the new drug. Understanding the mechanism of injury of hepatotoxins is essential to efficiently...

Descripción completa

Detalles Bibliográficos
Autores principales: Martínez-Sena, Teresa, Moro, Erika, Moreno-Torres, Marta, Quintás, Guillermo, Hengstler, Jan, Castell, José V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182947/
https://www.ncbi.nlm.nih.gov/pubmed/37022445
http://dx.doi.org/10.1007/s00204-023-03474-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182947/
https://www.ncbi.nlm.nih.gov/pubmed/37022445
http://dx.doi.org/10.1007/s00204-023-03474-8

Ejemplares similares