Structure of a eukaryotic cholinephosphotransferase-1 reveals mechanisms of substrate recognition and catalysis

Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotic cell membranes. In eukaryotes, two highly homologous enzymes, cholinephosphotransferase-1 (CHPT1) and choline/ethanolamine phosphotransferase-1 (CEPT1) catalyze the final step of de novo PC synthesis. CHPT1/CEPT1 joins two subs...

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Detalles Bibliográficos
Autores principales: Wang, Lie, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182977/
https://www.ncbi.nlm.nih.gov/pubmed/37179328
http://dx.doi.org/10.1038/s41467-023-38003-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182977/
https://www.ncbi.nlm.nih.gov/pubmed/37179328
http://dx.doi.org/10.1038/s41467-023-38003-9

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