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Hypoxia-mediated promotion of glucose metabolism in non-small cell lung cancer correlates with activation of the EZH2/FBXL7/PFKFB4 axis

F-box/LRR-repeat protein 7 (FBXL7) was predicted as a differentially expressed E3 ubiquitin ligase in non-small cell lung cancer (NSCLC), which has been suggested to influence cancer growth and metastasis. In this study, we aimed to decipher the function of FBXL7 in NSCLC and delineate the upstream...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Lin, Yang, Kang, Xiuhua, Liu, Zhicheng, Zou, Juntao, Xu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182982/
https://www.ncbi.nlm.nih.gov/pubmed/37179372
http://dx.doi.org/10.1038/s41419-023-05795-z