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Circ_0020256 induces fibroblast activation to drive cholangiocarcinoma development via recruitment of EIF4A3 protein to stabilize KLF4 mRNA

Cancer-associated fibroblasts (CAFs) are a kind of stromal cells in the cholangiocarcinoma (CCA) microenvironment, playing crucial roles in cancer development. However, the potential mechanisms of the interaction between CCA cells and CAFs remain obscure. This work investigated the role of circ_0020...

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Detalles Bibliográficos
Autores principales: Li, Zongyan, Chen, Zuxiao, Li, Shiying, Qian, Xiangjun, Zhang, Lei, Long, Guojie, Xie, Jiancong, Huang, Xiaoming, Zheng, Zheyu, Pan, Weidong, Li, Haiyan, Zhang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183031/
https://www.ncbi.nlm.nih.gov/pubmed/37179359
http://dx.doi.org/10.1038/s41420-023-01439-5