Cargando…

Circ_0020256 induces fibroblast activation to drive cholangiocarcinoma development via recruitment of EIF4A3 protein to stabilize KLF4 mRNA

Cancer-associated fibroblasts (CAFs) are a kind of stromal cells in the cholangiocarcinoma (CCA) microenvironment, playing crucial roles in cancer development. However, the potential mechanisms of the interaction between CCA cells and CAFs remain obscure. This work investigated the role of circ_0020...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zongyan, Chen, Zuxiao, Li, Shiying, Qian, Xiangjun, Zhang, Lei, Long, Guojie, Xie, Jiancong, Huang, Xiaoming, Zheng, Zheyu, Pan, Weidong, Li, Haiyan, Zhang, Dawei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183031/ https://www.ncbi.nlm.nih.gov/pubmed/37179359 http://dx.doi.org/10.1038/s41420-023-01439-5

Ejemplares similares

Tumor-associated macrophages promote cholangiocarcinoma progression via exosomal Circ_0020256
por: Chen, Shaoyi, et al.
Publicado: (2022)

KLF4 suppresses the proliferation of perihilar cholangiocarcinoma by negatively regulating GDF15 and phosphorylating AKT
por: Zhang, Xiaoming, et al.
Publicado: (2023)

circ-SIRT1 Promotes Colorectal Cancer Proliferation and EMT by Recruiting and Binding to eIF4A3
por: Wang, Xiangjie, et al.
Publicado: (2021)

CircETFA upregulates CCL5 by sponging miR-612 and recruiting EIF4A3 to promote hepatocellular carcinoma
por: Lu, Chen, et al.
Publicado: (2021)

Circular RNA circEIF3C promotes intrahepatic cholangiocarcinoma progression and immune evasion via the miR-34a-5p/B7–H4 axis
por: Zhong, Xiaoming, et al.
Publicado: (2022)

The Partial Role of KLF4 and KLF5 in Gastrointestinal Tumors
por: Li, Jun-Chen, et al.
Publicado: (2021)

Synergistic activation of eIF4A by eIF4B and eIF4G
por: Nielsen, Klaus H., et al.
Publicado: (2011)

Long-term results of ERCP- or PTCS-directed photodynamic therapy for unresectable hilar cholangiocarcinoma
por: Li, Zongyan, et al.
Publicado: (2020)

The duck hepatitis virus 5'-UTR possesses HCV-like IRES activity that is independent of eIF4F complex and modulated by downstream coding sequences
por: Liu, Guangqing, et al.
Publicado: (2011)

Circ_cse1l Inhibits Colorectal Cancer Proliferation by Binding to eIF4A3
por: Xu, Bin, et al.
Publicado: (2020)

Circ_0074027 binds to EIF4A3 and promotes gastric cancer progression
por: Wu, Yuluo, et al.
Publicado: (2021)

eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle
por: Harms, Ulf, et al.
Publicado: (2014)

circKLF4 Upregulates Klf4 and Endoglin to Promote Odontoblastic Differentiation of Mouse Dental Papilla Cells via Sponging miRNA-1895 and miRNA-5046
por: Zhang, Yue, et al.
Publicado: (2022)

The Role of KLF(4) in Alzheimer’s Disease
por: Cheng, Ziqian, et al.
Publicado: (2018)

Knockdown of circSMAD2 inhibits the tumorigenesis of gallbladder cancer through binding with eIF4A3
por: Qin, Yiyu, et al.
Publicado: (2021)

Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions
por: Yoffe, Yael, et al.
Publicado: (2009)

Regulatory Mechanism of circEIF4G2 Targeting miR-26a in Acute Myocardial Infarction
por: Zhang, Zaiyong, et al.
Publicado: (2022)

Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E
por: Ma, Xuhui, et al.
Publicado: (2019)

CircEIF4G2 Promotes Tumorigenesis and Progression of Osteosarcoma by Sponging miR-218
por: Lin, Erhu, et al.
Publicado: (2020)

Loss-of-Function Analysis Reveals Distinct Requirements of the Translation Initiation Factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila Spermatogenesis
por: Ghosh, Sanjay, et al.
Publicado: (2015)

Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F
por: Chu, Jennifer, et al.
Publicado: (2020)

KLF4α stimulates breast cancer cell proliferation by acting as a KLF4 antagonist
por: Ferralli, Jacqueline, et al.
Publicado: (2016)

Human eukaryotic initiation factor 4E (eIF4E) and the nucleotide-bound state of eIF4A regulate eIF4F binding to RNA
por: Izidoro, Mario Servulo, et al.
Publicado: (2022)

SOX2 recruits KLF4 to regulate nasopharyngeal carcinoma proliferation via PI3K/AKT signaling
por: Tang, Jianming, et al.
Publicado: (2018)

SUMO-2 Promotes mRNA Translation by Enhancing Interaction between eIF4E and eIF4G
por: Chen, Li-zhao, et al.
Publicado: (2014)

circEIF4G2 modulates the malignant features of cervical cancer via the miR-218/HOXA1 pathway
por: Mao, Yifan, et al.
Publicado: (2019)

Circular RNA circEIF4G2 aggravates renal fibrosis in diabetic nephropathy by sponging miR‐218
por: Xu, Bojin, et al.
Publicado: (2020)

CircTADA2A suppresses the progression of colorectal cancer via miR-374a-3p/KLF14 axis
por: Li, Zhen, et al.
Publicado: (2020)

KLF4 transcription factor in tumorigenesis
por: He, Zhihong, et al.
Publicado: (2023)

Selectivity for eIF4E
por: LeBrasseur, Nicole
Publicado: (2005)

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction
por: Zheng, Rui, et al.
Publicado: (2022)

Translation, Pdcd4 and eIF4A
por: Biyanee, Abhiruchi, et al.
Publicado: (2015)

circUBAP2 exacerbates malignant capabilities of NSCLC by targeting KLF4 through miR-3182 modulation
por: Zheng, Guanying, et al.
Publicado: (2021)

YY1 and eIF4A3 are mediators of the cell proliferation, migration and invasion in cholangiocarcinoma promoted by circ-ZNF609 by targeting miR-432-5p to regulate LRRC1
por: Guan, Canghai, et al.
Publicado: (2021)

Effect of Photodynamic Therapy on Gemcitabine-Resistant Cholangiocarcinoma in vitro and in vivo Through KLF10 and EGFR
por: Yang, Yang, et al.
Publicado: (2021)

The Initiation Factors eIF2, eIF2A, eIF2D, eIF4A, and eIF4G Are Not Involved in Translation Driven by Hepatitis C Virus IRES in Human Cells
por: González-Almela, Esther, et al.
Publicado: (2018)

EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis
por: Wang, Kun, et al.
Publicado: (2021)

Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission
por: Ma, Dong, et al.
Publicado: (2020)

Human Translation Initiation Factor eIF4G1 Possesses a Low-Affinity ATP Binding Site Facing the ATP-Binding Cleft of eIF4A in the eIF4G/eIF4A Complex
por: Akabayov, Sabine R., et al.
Publicado: (2014)

eIF4E3 forms an active eIF4F complex during stresses (eIF4F(S)) targeting mTOR and re-programs the translatome
por: Weiss, Benjamin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o9ih4glfnvtv3r0idkgv3qk7h3