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Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome

Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder characterized by chronic low-grade inflammation. Previous studies have demonstrated that the gut microbiome can affect the host tissue cells’ mRNA N6-methyladenosine (m6A) modifications. This study aimed to understand the role o...

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Detalles Bibliográficos
Autores principales: Liu, Kailu, He, Xi, Huang, Jingyu, Yu, Simin, Cui, Meiting, Gao, Mengya, Liu, Li, Qian, Yu, Xie, Ying, Hui, Miao, Hong, Yanli, Nie, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183145/
https://www.ncbi.nlm.nih.gov/pubmed/37179374
http://dx.doi.org/10.1186/s13148-023-01487-9