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Optimization, and biological evaluation of 3-O-β-chacotriosyl betulinic acid amide derivatives as novel small-molecule Omicron

SARS-CoV-2 Omicron viruses possess a high antigenic shift, and the approved anti-SARS-CoV-2 drugs are extremely limited, which makes the development of new antiviral drugs for the clinical treatment and prevention of SARS-CoV-2 outbreaks imperative. We have previously discovered a new series of mark...

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Detalles Bibliográficos
Autores principales: Liu, Mingjian, Wang, Jinshen, Shi, Shanshan, Gao, Yongfeng, Zhang, Yixiao, Yuan, Ziying, Huang, Enlin, Li, Sumei, Liu, Shuwen, Song, Gaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183356/
https://www.ncbi.nlm.nih.gov/pubmed/37209612
http://dx.doi.org/10.1016/j.ejmech.2023.115463