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Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures

Coronary artery disease (CAD) is a pandemic disease where up to half of the risk is explained by genetic factors. Advanced insights into the genetic basis of CAD require deeper understanding of the contributions of different cell types, molecular pathways, and genes to disease heritability. Here, we...

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Detalles Bibliográficos
Autores principales: Örd, Tiit, Lönnberg, Tapio, Nurminen, Valtteri, Ravindran, Aarthi, Niskanen, Henri, Kiema, Miika, Õunap, Kadri, Maria, Maleeha, Moreau, Pierre R., Mishra, Pashupati P., Palani, Senthil, Virta, Jenni, Liljenbäck, Heidi, Aavik, Einari, Roivainen, Anne, Ylä-Herttuala, Seppo, Laakkonen, Johanna P., Lehtimäki, Terho, Kaikkonen, Minna U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183377/
https://www.ncbi.nlm.nih.gov/pubmed/37060905
http://dx.doi.org/10.1016/j.ajhg.2023.03.013