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Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures
Coronary artery disease (CAD) is a pandemic disease where up to half of the risk is explained by genetic factors. Advanced insights into the genetic basis of CAD require deeper understanding of the contributions of different cell types, molecular pathways, and genes to disease heritability. Here, we...
Autores principales: | Örd, Tiit, Lönnberg, Tapio, Nurminen, Valtteri, Ravindran, Aarthi, Niskanen, Henri, Kiema, Miika, Õunap, Kadri, Maria, Maleeha, Moreau, Pierre R., Mishra, Pashupati P., Palani, Senthil, Virta, Jenni, Liljenbäck, Heidi, Aavik, Einari, Roivainen, Anne, Ylä-Herttuala, Seppo, Laakkonen, Johanna P., Lehtimäki, Terho, Kaikkonen, Minna U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183377/ https://www.ncbi.nlm.nih.gov/pubmed/37060905 http://dx.doi.org/10.1016/j.ajhg.2023.03.013 |
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