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Biology and impact of lineage plasticity in ALK-positive NSCLC: a narrative review
BACKGROUND AND OBJECTIVE: Lineage transformation is a known mechanism of acquired resistance to targeted therapies in non-small cell lung cancer (NSCLC). Transformation to small cell and squamous carcinoma and epithelial-to-mesenchymal transition (EMT) have all been identified as recurrent but rare...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183401/ https://www.ncbi.nlm.nih.gov/pubmed/37197622 http://dx.doi.org/10.21037/tlcr-22-867 |