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Biology and impact of lineage plasticity in ALK-positive NSCLC: a narrative review

BACKGROUND AND OBJECTIVE: Lineage transformation is a known mechanism of acquired resistance to targeted therapies in non-small cell lung cancer (NSCLC). Transformation to small cell and squamous carcinoma and epithelial-to-mesenchymal transition (EMT) have all been identified as recurrent but rare...

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Detalles Bibliográficos
Autores principales: Meador, Catherine B., Piotrowska, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183401/
https://www.ncbi.nlm.nih.gov/pubmed/37197622
http://dx.doi.org/10.21037/tlcr-22-867