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False positivity in break apart fluorescence in-situ hybridization due to polyploidy

BACKGROUND: In-situ hybridization (ISH) is a diagnostic tool in the detection of chromosomal anomalies, which has important implications for diagnosis, classification and prediction of cancer therapy in various diseases. Certain thresholds of number of cells showing an aberrant pattern are commonly...

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Detalles Bibliográficos
Autores principales: van Gulik, Anna Lena, Sluydts, Ellen, Vervoort, Liesbet, Kockx, Mark, Kortman, Pim, Ylstra, Bauke, Finn, Stephen P., Bubendorf, Lukas, Bahce, Idris, Sie, Daoud, Radonic, Teodora, Lissenberg-Witte, Birgit, Thunnissen, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183404/
https://www.ncbi.nlm.nih.gov/pubmed/37197629
http://dx.doi.org/10.21037/tlcr-22-516