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Desulfovibrio bacteria enhance alpha-synuclein aggregation in a Caenorhabditis elegans model of Parkinson’s disease

INTRODUCTION: The aggregation of the neuronal protein alpha-synuclein (alpha-syn) is a key feature in the pathology of Parkinson’s disease (PD). Alpha-syn aggregation has been suggested to be induced in the gut cells by pathogenic gut microbes such as Desulfovibrio bacteria, which has been shown to...

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Detalles Bibliográficos
Autores principales: Huynh, Vy A., Takala, Timo M., Murros, Kari E., Diwedi, Bidhi, Saris, Per E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183572/
https://www.ncbi.nlm.nih.gov/pubmed/37197200
http://dx.doi.org/10.3389/fcimb.2023.1181315