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Lynch syndrome: from detection to treatment

Lynch syndrome (LS) is an inherited cancer predisposition syndrome associated with high lifetime risk of developing tumours, most notably colorectal and endometrial. It arises in the context of pathogenic germline variants in one of the mismatch repair genes, that are necessary to maintain genomic s...

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Detalles Bibliográficos
Autores principales: Williams, Madeleine H., Hadjinicolaou, Andreas V., Norton, Benjamin C., Kader, Rawen, Lovat, Laurence B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183578/
https://www.ncbi.nlm.nih.gov/pubmed/37197422
http://dx.doi.org/10.3389/fonc.2023.1166238