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Lynch syndrome: from detection to treatment
Lynch syndrome (LS) is an inherited cancer predisposition syndrome associated with high lifetime risk of developing tumours, most notably colorectal and endometrial. It arises in the context of pathogenic germline variants in one of the mismatch repair genes, that are necessary to maintain genomic s...
Autores principales: | Williams, Madeleine H., Hadjinicolaou, Andreas V., Norton, Benjamin C., Kader, Rawen, Lovat, Laurence B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183578/ https://www.ncbi.nlm.nih.gov/pubmed/37197422 http://dx.doi.org/10.3389/fonc.2023.1166238 |
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