Cargando…

A high-concentrate diet induces inflammatory injury via regulating Ca(2+)/CaMKKβ-mediated autophagy in mammary gland tissue of dairy cows

INTRODUCTION: Calmodulin-dependent protein kinase β (CaMKKβ) is closely related to Ca(2+) concentration. An increase in Ca(2+) concentration in the cytoplasm activates CaMKKβ, and activated CaMKKβ affects the activities of AMPK and mTOR and induces autophagy. A high-concentrate diet leads to Ca(2+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Meijuan, Li, Xuerui, Wang, Zihan, Huo, Ran, Ma, Nana, Chang, Guangjun, Shen, Xiangzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183583/
https://www.ncbi.nlm.nih.gov/pubmed/37197665
http://dx.doi.org/10.3389/fimmu.2023.1186170