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A high-concentrate diet induces inflammatory injury via regulating Ca(2+)/CaMKKβ-mediated autophagy in mammary gland tissue of dairy cows
INTRODUCTION: Calmodulin-dependent protein kinase β (CaMKKβ) is closely related to Ca(2+) concentration. An increase in Ca(2+) concentration in the cytoplasm activates CaMKKβ, and activated CaMKKβ affects the activities of AMPK and mTOR and induces autophagy. A high-concentrate diet leads to Ca(2+)...
Autores principales: | Meng, Meijuan, Li, Xuerui, Wang, Zihan, Huo, Ran, Ma, Nana, Chang, Guangjun, Shen, Xiangzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183583/ https://www.ncbi.nlm.nih.gov/pubmed/37197665 http://dx.doi.org/10.3389/fimmu.2023.1186170 |
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