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Regulatory T cells in peripheral tissue tolerance and diseases
Maintenance of peripheral tolerance by CD4(+)Foxp3(+) regulatory T cells (Tregs) is essential for regulating autoreactive T cells. The loss of function of Foxp3 leads to autoimmune disease in both animals and humans. An example is the rare, X-linked recessive disorder known as IPEX (Immune Dysregula...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183596/ https://www.ncbi.nlm.nih.gov/pubmed/37197653 http://dx.doi.org/10.3389/fimmu.2023.1154575 |