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Regulatory T cells in peripheral tissue tolerance and diseases

Maintenance of peripheral tolerance by CD4(+)Foxp3(+) regulatory T cells (Tregs) is essential for regulating autoreactive T cells. The loss of function of Foxp3 leads to autoimmune disease in both animals and humans. An example is the rare, X-linked recessive disorder known as IPEX (Immune Dysregula...

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Detalles Bibliográficos
Autores principales:	Cheru, Nardos, Hafler, David A., Sumida, Tomokazu S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183596/ https://www.ncbi.nlm.nih.gov/pubmed/37197653 http://dx.doi.org/10.3389/fimmu.2023.1154575

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