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Inhibition of DAI refrains dendritic cells from maturation and prolongs murine islet and skin allograft survival

INTRODUCTION: Central to allograft rejection is the T cell-mediated adaptive immune response initiated by activated dendritic cells (DCs). Previous studies have shown that the DNA-dependent activator of IFN regulatory factors (DAI) is involved in the maturation and activation of DCs. Therefore, we h...

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Detalles Bibliográficos
Autores principales: Cheng, Pengrui, Jian, Qian, Fu, Zongli, Deng, Ronghai, Ma, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183602/
https://www.ncbi.nlm.nih.gov/pubmed/37197662
http://dx.doi.org/10.3389/fimmu.2023.1182851