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Inhibition of DAI refrains dendritic cells from maturation and prolongs murine islet and skin allograft survival
INTRODUCTION: Central to allograft rejection is the T cell-mediated adaptive immune response initiated by activated dendritic cells (DCs). Previous studies have shown that the DNA-dependent activator of IFN regulatory factors (DAI) is involved in the maturation and activation of DCs. Therefore, we h...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183602/ https://www.ncbi.nlm.nih.gov/pubmed/37197662 http://dx.doi.org/10.3389/fimmu.2023.1182851 |