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RIPK1 and RIPK3 are positive prognosticators for cervical cancer patients and C2 ceramide can inhibit tumor cell proliferation in vitro

INTRODUCTION: The enzymes Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) und 3 (RIPK3) as well as the protein Mixed lineage kinase domain like pseudokinase (pMLKL) play a role in the signaling cascade of necroptosis. This is a form of programmed cell death which is caspase-independen...

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Detalles Bibliográficos
Autores principales: Vogelsang, Tilman L. R., Kast, Verena, Bagnjuk, Konstantin, Eubler, Katja, Jeevanandan, Sree Priyanka, Schmoeckel, Elisa, Trebo, Anna, Topalov, Nicole Elisabeth, Mahner, Sven, Mayr, Doris, Mayerhofer, Artur, Jeschke, Udo, Vattai, Aurelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183606/
https://www.ncbi.nlm.nih.gov/pubmed/37197430
http://dx.doi.org/10.3389/fonc.2023.1110939