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WHSC1 is involved in DNA damage, cellular senescence and immune response in hepatocellular carcinoma progression

Wolf–Hirschhorn syndrome candidate 1 (WHSC1) is a transcriptional regulatory protein that encodes a histone methyltransferase to control H3K36me2 modification. WHSC1 was upregulated and associated with poor prognosis in HCC. The elevated WHSC1 likely due to the alterations of DNA methylation or RNA...

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Detalles Bibliográficos
Autores principales: Yan, Jia, Zhang, Ming Yang, Lin, Jing, Li, Ke Xin, Zhao, Zhi Min, Gao, Yu Min, Deng, Xiu Ling, Wang, Chang Shan, Wang, Hai Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183708/
https://www.ncbi.nlm.nih.gov/pubmed/37073435
http://dx.doi.org/10.1111/jcmm.17743